158 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
progressive fibrosis of skin ... LcSSc) - distal skin ... DcSSc; diffuse) - skin ... changes): skin ... #diagnosis #signs
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Diagnosis Algorithm ... Primary Causes ... == Primary Skin ... • Xerosis (dry skin ... == No Primary Skin
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Diagnosis Framework ... thrombophlebitis Skin ... band syndrome • Shin ... Brittle nails - Skin ... skin • Inflammation
Systemic Sclerosis Associated Autoantibodies
Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis
Anti-centromere: Limited skin disease (~93-95%), Pulmonary
anti-Sc170): Diffuse skin ... Anti-centromere: Limited skin ... Rapid progressive skin ... Autoantibodies #diagnosis ... #rheumatology
Skin Hypopigmentation - Differential Diagnosis Algorithm

Diffuse Congenital - Generalized hypopigmentation of hair, eyes, skin
 • Phenylketonuria
Skin Hypopigmentation ... - Differential ... of hair, eyes, skin ... Hypopigmentation #disorders #skin ... #causes
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features of Systemic ... Sjögrens (15%) Skin ... Polyneuropathy, Cranial nerve ... signs #symptoms #diagnosis ... #rheumatology
Pruritus - Primary Skin Lesion - Differential Diagnosis Algorithm
Macules / Papules / Plaques:
 • Xerosis (dry
Pruritus - Primary Skin ... Lesion - Differential ... Diagnosis Algorithm ... • Xerosis (dry skin ... #causes
Vascular Skin Lesions - Differential Diagnosis Algorithm
 - Petechiae < 0.2 cm diameter
 - Purpura 0.2
Vascular Skin Lesions ... - Differential ... Diagnosis Algorithm ... discolorations of skin ... #causes
Dematoses in Pregnancy - Specific Skin Conditions
Non-Pruritic
 • Pustular psoriasis of pregnancy
 • Impetigo Herpetiformis
Pruritic -
Pregnancy - Specific Skin ... - Non-Primary Skin ... Pruritic - Primary Skin ... #Diagnosis #Algorithm ... #causes
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
Vesiculobullous Skin ... Rash - Differential ... Diagnosis Algorithm ... • Bullous systemic ... #causes