114 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
progressive fibrosis of skin ... LcSSc) - distal skin ... DcSSc; diffuse) - skin ... changes): skin ... Scleroderma #SSc #rheumatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
and Primary Causes ... == Primary Skin ... • Xerosis (dry skin ... == No Primary Skin ... #generalized #dermatology
Systemic Sclerosis Associated Autoantibodies
Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis
Anti-centromere: Limited skin disease (~93-95%), Pulmonary
Systemic Sclerosis ... anti-Sc170): Diffuse skin ... Anti-centromere: Limited skin ... Rapid progressive skin ... Autoantibodies #diagnosis #rheumatology
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Leg Pain - Differential ... thrombophlebitis Skin ... band syndrome • Shin ... Brittle nails - Skin ... skin • Inflammation
Skin Hypopigmentation - Differential Diagnosis Algorithm

Diffuse Congenital - Generalized hypopigmentation of hair, eyes, skin
 • Phenylketonuria
Skin Hypopigmentation ... of hair, eyes, skin ... Hypopigmentation #disorders #skin ... #dermatology #Differential ... Diagnosis #Algorithm #causes
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Skin Conditions ... Scleroderma Thickened skin ... arthritis Discoid skin ... #joint #pain #skin ... #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features of Systemic ... Sjögrens (15%) Skin ... joints Nervous system ... Polyneuropathy, Cranial nerve ... symptoms #diagnosis #rheumatology
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Involving the Skin ... - Differential ... Vasculitis Skin ... Cutaneous #Vasculitis #skin ... #dermatology #rheumatology
Dematoses in Pregnancy - Specific Skin Conditions
Non-Pruritic
 • Pustular psoriasis of pregnancy
 • Impetigo Herpetiformis
Pruritic -
Pregnancy - Specific Skin ... - Non-Primary Skin ... Pruritic - Primary Skin ... #Differential # ... Diagnosis #Algorithm #causes
Pruritus - Primary Skin Lesion - Differential Diagnosis Algorithm
Macules / Papules / Plaques:
 • Xerosis (dry
Pruritus - Primary Skin ... Lesion - Differential ... • Xerosis (dry skin ... #Differential # ... Diagnosis #Algorithm #causes