28 results
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Leg Pain - Differential ... thrombophlebitis Skin ... • Shin splints ... Brittle nails - Skin ... skin • Inflammation
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Causes == Primary Skin ... • Xerosis (dry skin ... == No Primary Skin ... Hyperthyroidism CBC ... Myelodisplastic syndrome
Clonorchiasis - Clonorchis sinensis Life Cycle
1) Embryonated eggs passed in feces.
2) Eggs ingested by the snail
encyst in the skin ... Metacercariae in flesh or skin ... LifeCycle #diagnosis #pathophysiology ... #infectiousdiseases ... #cdc #parasite
Leishmaniasis Life Cycle
1) Sandfly takes a blood meal (injects promastigote stage into the skin)
Human Stages:
2) Promastigotes
stage into the skin ... LifeCycle #diagnosis #pathophysiology ... #infectiousdiseases ... #cdc #parasite
Intestinal Hookworm Life Cycle
1) Eggs in feces
2) Rhabditiform larva hatches
3) Development to filariform larva in environment
4)
larva penetrates skin ... lifecycle #diagnosis #pathophysiology ... #infectiousdiseases ... #cdc #parasite
Strongyloides fuelleborni Lifecycle
Free-Living Cycle
1) Eggs containing rhabditiform larvae passed in feces.
2) Rhabditiform larvae hatch in environment.
penetrate the intact skin ... Parasite #diagnosis #pathophysiology ... #infectiousdiseases ... #cdc
Onchocerciasis - Onchocerca volvulus Life Cycle
1) Blackfly (genus Simulium) takes a blood meal (L3 larvae enter
typically are found in skin ... LifeCycle #diagnosis #pathophysiology ... #infectiousdiseases ... #cdc #parasite
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Purpura, ischemic skin ... - Affects the skin ... Cryoglobulinemic Vasculitis - Skin ... glomerular ischemia - Skin ... Small Vessels: Skin
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
Toxoplasmosis (CD4 ... Diagnosis- Compatible syndrome ... , may also see skin ... CNS Lymphoma (CD4 ... Lesions #Brain #differential
Strongyloides Stercoralis Lifecycle
Free-Living Cycle:
1) Rhabditiform larvae in the intestine are excreted in stool. 
2) Development into
penetrate the intact skin ... intestinal mucosa (or skin ... LifeCycle #diagnosis #pathophysiology ... #infectiousdiseases ... #cdc #parasite