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diagnosis differential rheumatology dermatology management algorithm causes clinical erythematosus lupus pruritus secondary signs sle symptoms vasculitides behcet classification conditions disease
Small Vessel Vasculitides • Granulomatosis with polyangiitis - Granulomatous manifestations (e.g., nasal crusting, destructive sinusitis, pulmonary
Small Vessel Vasculitides ... and C viruses. systemic ... and Sjogren's syndrome ... in absence of skin ... #vasculitis #differential
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... Causes == Primary Skin ... • Xerosis (dry skin ... == No Primary Skin ... Myelodisplastic syndrome
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Purpura, ischemic skin ... - Affects the skin ... - Skin, glomeruli ... glomerular ischemia - Skin ... Small Vessels: Skin
Pyoderma Gangrenosum: Autoimmune disorder resulting in a vasculitis which causes slowly progressive ulceration of the skin.
resulting in a vasculitis ... ulceration of the skin ... a number of systemic ... Images #Clinical #Photo ... #Dermatology #SkinRash
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features of Systemic ... Sjögrens (15%) Skin ... Butterfly rash, Vasculitis ... Polyneuropathy, Cranial nerve ... Demyelinating syndromes
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Purpura, ischemic skin ... • Affects the skin ... cmpkx deposits skin ... : • Skin lesions
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... Muscle weakness (generalized ... central nervous system ... Peripheral Nervous System ... #Weakness #Differential
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... Autoimmunity: • -MM/WM: Vasculitis ... Hypergammaglobulinemic macular Vasculitis ... Hematology #Monoclonal #Differential
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... response to local skin ... retinal damage) • Skin ... test (this is a skin ... Behcet disease) Differential
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Eosinophilia and Systemic ... characterized by extensive skin ... Skin involvement ... Resolution > 15 days Differentials ... SJS/TEN • Acute Generalized
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