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diagnosis differential dermatology management clinical algorithm causes syndrome vasculitis skin erythematosus lupus oncology photo secondary signs sle symptoms treatment ana
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
LcSSc) - distal skin ... DcSSc; diffuse) - skin ... salt and pepper" skin ... changes): skin ... #SSc #rheumatology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic Diseases ... connective tissue disease ... sclerosis/scleroderma ... ANA #patterns #rheumatology ... #diagnosis #differential
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Skin Conditions ... Thickened skin ... arthritis Discoid skin ... #joint #pain #skin ... #diagnosis #rheumatology
Systemic Sclerosis Associated Autoantibodies Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis Anti-centromere: Limited skin disease (~93-95%), Pulmonary
Systemic Sclerosis ... anti-Sc170): Diffuse skin ... Anti-centromere: Limited skin ... Rapid progressive skin ... Autoantibodies #diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
sclerosis/scleroderma ... sclerosis/scleroderma ... sclerosis/scleroderma ... ANA #patterns #rheumatology ... #diagnosis #differential
Scleroderma Associated Telangiectasia. If you see them-round, often well circumscribed (but can be matte-like too) &
Scleroderma Associated ... & blanchable, differential ... Telangiectasia #clinical #video ... #blanching #skin ... #dermatology #rheumatology
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 Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features of Systemic ... Sjögrens (15%) Skin ... Polyneuropathy, Cranial nerve ... pain (20%) Renal disease ... symptoms #diagnosis #rheumatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Causes == Primary Skin ... • Xerosis (dry skin ... == No Primary Skin ... Cholestatic liver disease ... #generalized #dermatology
Pyoderma Gangrenosum: Autoimmune disorder resulting in a vasculitis which causes slowly progressive ulceration of the skin.
ulceration of the skin ... a number of systemic ... diseases, it is ... Clinical #Photo #Dermatology ... #SkinRash #Pyoderma
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
eosinophilia, skin ... Full-thickness skin ... over thickened skin ... Lichen planus-like skin ... or generalized skin
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