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diagnosis rheumatology differential dermatology erythematosus lupus oncology signs systemic vasculitis algorithm allergy arthropathies arthropathy behcet chronic classification cll disease dress
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
- Differential Diagnosis ... arthritis - (Reiter’s syndrome ... arthritis - with the skin ... Erythematosus (SLE ... should have other symptoms
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... Splenomegaly - CTD (SLE ... Kasabach-Merritt syndrome ... Associated - SLE
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Systemic Lupus (SLE ... Sjögrens (15%) Skin ... Polyneuropathy, Cranial nerve ... Demyelinating syndromes ... erythematosus #signs #symptoms
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
response to local skin ... retinal damage) • Skin ... test (this is a skin ... Behcet disease) Differential ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... permanent alopecia Differential ... Malignancy (e.g. hematologic ... Seizures • Strokes Skin ... Induced Lupus: • Symptoms
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
characterized by extensive skin ... Symptoms: • The ... Skin involvement ... Resolution > 15 days Differentials ... SinaiBmoreIMRes #DRESS #Syndrome
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Purpura, ischemic skin ... - Affects the skin ... Cryoglobulinemic Vasculitis - Skin ... glomerular ischemia - Skin ... Small Vessels: Skin
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Purpura, ischemic skin ... commonly affects the skin ... • Affects the skin ... cmpkx deposits skin ... Vasculitis: • Skin
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... with no early symptoms ... Hepatomegaly • Skin ... lymphoproliferative disorders ... workup #oncology #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... overlaps with RA, SLE ... amyloidosis, PAH Skin ... : • Dry skin (xerosis ... Diagnosis #Management
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