39 results
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... / Symptoms: - ... Xeroderma (Dry skin ... #Syndrome #Pathophysiology ... #Symptoms
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Diagnosis Algorithm ... Skin Lesions == ... • Xerosis (dry skin ... Skin Lesion / Systemic ... #Diagnosis #Algorithm
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
LcSSc) - distal skin ... DcSSc; diffuse) - skin ... Hepatic: PBC (primary ... salt and pepper" skin ... changes): skin
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Joint Disorders - Differential ... Diagnosis Algorithm ... arthritis - with the skin ... should have other symptoms ... Joint #Disorders #msk
CLINICAL MANIFESTATIONS 
OF ADRENAL INSUFFICIENCY. 

Primary and secondary adrenal insufficiency:
 - Tiredness, weakness, mental depression
Primary and secondary ... eosinophilia Primary ... Autoimmune thyroid disease ... disorders: - Pale skin ... Insufficiency #Signs
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
Clinical: • Disease ... neuropathies • Skin ... dysrhythmias • Ophthalmologic ... Sarcoidosis #Diagnosis #Symptoms ... #Signs #Pulmonary
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... failure PBC Signs ... and Symptoms: ... Examination: • Skin ... bile ducts Differential
Differential Diagnosis and Evaluation of Hyponatremia:
1) Identification of onset (acute vs. chronic)
2) Presence of symptoms (HA,
Differential Diagnosis ... 2) Presence of symptoms ... status (edema, JVD, skin ... , liver, renal disease ... #Algorithm #Ddxof
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic Algorithm ... Ill-appearing, vital sign ... sulfa-drug - Skin ... Color #Targetoid #Algorithm ... #Differential #
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
intervertebral disc disease ... MeralgiaParesthetica #MSK ... #pathophysiology ... #differential # ... diagnosis #signs