12 results
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Dermatomyositis ... processes occur in the skin ... -> Heliotrope Rash ... Pathophysiology #Signs ... #Symptoms #Vasculitis
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Syndrome) is a skin ... inflamed or blistered skin ... development of skin ... deeper into the skin ... small samples of skin
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
characterized by extensive skin ... rash in association ... Symptoms: • The ... Skin involvement ... Resolution > 15 days Differentials
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... retinal damage) • Skin ... test (this is a skin ... Behcet disease) Differential ... #signs #symptoms
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
fatigue Heat Rash ... blisters on the skin ... → Syncope • Signs ... /Symptoms: - Lightheadedness ... Pale and sweaty skin
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
have typical DM skin ... (blue-purple) rash ... ulcerations • Skin ... ulcerations • Auricular skin ... #diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Purpura, ischemic skin ... - Affects the skin ... Cryoglobulinemic Vasculitis - Skin ... glomerular ischemia - Skin ... Small Vessels: Skin
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Purpura, ischemic skin ... commonly affects the skin ... • Affects the skin ... cmpkx deposits skin ... Vasculitis: • Skin
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... permanent alopecia Differential ... Still disease, dermatomyositis ... Seizures • Strokes Skin ... Induced Lupus: • Symptoms
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... Self-limiting, chronic but stable ... nodes: 13-15%, skin ... Sarcoidosis #Diagnosis #Management ... #Signs #Symptoms