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cardiology pharmacology antiarrhythmics classes actions adrenergic adrenoceptor allergy comparison contraction cycle diagnosis hypersensitivity myocyte phases reactions receptors types vaughan williams
Cardiac Myocyte Contractile cycle - Ca2+ binds to TnC → TnI is inhibited → conformational change
Cardiac Myocyte Contractile ... progressively shorten ... #Pathophysiology ... Cardiology #Myocyte #Contractile ... #Cycle #Contraction
Antiarrhythmics Pharmacology Summary Cardiac Conduction Phases: Phase 0 - Ventricular Depolarization: • Na+ channels open leading to a
influx initiating contraction ... occurs initiating contraction ... Vaughan Williams Classification ... #Pharmacology #Classification ... #Classes #pathophysiology
Antiarrhythmics - Vaughan Williams Classification: CLASS 1 - Sodium Channel Blockers: • MOA: Block fast Na+ channels
Vaughan Williams Classification ... repolarization - ↓ contraction ... #Pharmacology #Classification ... #Classes #pathophysiology
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Hypersensitivity #Types #Classification ... #Pathophysiology ... Diagnosis #Reactions #Table
Adrenoceptor Actions α1 • Vascular smooth muscle - Contraction • Genitourinary smooth muscle - Contraction • Intestinal
smooth muscle - Contraction ... smooth muscle - Contraction ... smooth muscle - Contraction ... #pharmacology #pathophysiology ... #comparison #table
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