10 results
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Pathophysiology ... deficit: - Type I DM ... produced - Type II DM ... #dka #hhs #pathophysiology ... #comparison #endocrinology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... Inverse Gottron’s sign ... 74% of anti-MDA5 DM ... lesser extent, DM ... • Anti-MDA5 DM
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Dermatomyositis ... (DM) and Polymyositis ... #DM #Polymyositis ... PM #Diagnosis #Pathophysiology ... #Signs #Symptoms
Tweetorial - How does diabetes mellitus (DM) lead to an increased risk of infection? 

By Dr.
diabetes mellitus (DM ... Risk #Tweetorial #Endocrinology ... #DM #Pathophysiology
Holster Sign in Dermatomyositis

Interestingly, poikiloderma and violaceous erythema can occur in sun protected areas as well
Holster Sign in ... Dermatomyositis ... of DM located along ... called: The holster sign ... Thighs #SkinRash #Dermatomyositis
Psoriasiform Scalp Findings in Dermatomyositis

Scalp: DM patients can present with a psoriasiform scalp eruption characterized redness,
Scalp Findings in Dermatomyositis ... Scalp: DM patients ... the presenting sign ... Psoriasiform #Scalp #sign ... #Dermatomyositis
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
polyneuropathy: DM ... Mononeuritis multiplex (DM ... Lack of UMN/LMN signs ... Muscle Biopsy: Dermatomyositis
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Insulin resist + DM ... malignancy Pathophysiology ... Pegvisomant) ± D2 ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
Anti-NXP-2 Dermatomyositis ... DM with generalized ... to have typical DM ... chest (in a V-sign ... shoulders (in a shawl sign
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
levels • EMG DERMATOMYOSITIS ... 140 (amyopathic dermatomyositis ... papules and Gottron sign ... ) • Shawl sign ... elevated < PM and DM