25 results
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
Brudzinski’s Sign ... Brudzinski's sign ... While the pathophysiology ... despite severe disease ... PhysicalExam #Pediatrics #Peds
Keratoconus: Pathogenesis and Clinical Findings
Genetics
 • Family history of keratoconus
 • Ehlers-Danlos syndrome
 • Down, Turner,
rubbing • Atopic diseases ... > Keratoconus Signs ... Ring • Munson's sign ... • Rizutti's Sign ... #ophthalmology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... cases Clinical Signs ... years - May have signs ... decreased reflexes Pathophysiology ... CMC_IM #Potts #Disease
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Diagnosis and Management ... When present, symptoms ... , signs, and complications ... von Willebrand disease ... PV #Diagnosis #Management
Management of Serotonin Syndrome
Identify and stop all serotoninergic medications
 • Avoid inadvertent Rx of serotoninergic meds
Management of Serotonin ... serotoninergic meds ... normalize vital signs ... then 2 mg q2h if symptoms ... #treatment #toxicology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... TLS #diagnosis #management
Optic Neuritis - Diagnosis and Management
 • Epidemiology: Female (75%), 18-50 years,
caucasian
 • Symptoms: Moderate visual
Diagnosis and Management ... caucasian • Symptoms ... Unilateral • Signs ... other auto-immune diseases ... #ophthalmology
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
variability in disease ... mood - Primary treatment ... MoodDisorders #Diagnosis #Pathophysiology ... #Signs #Symptoms
Emphysematous Cystitis
Epidemiology:
 • Usually middle-aged diabetic women
 • Other RF: neurogenic bladder, urinary tract outlet obstruction,
compromise Clinical Signs ... /Symptoms: • Usually ... be present or signs ... Pathophysiology: ... data • Early treatment