11 results
diagnosis hematology oncology differential leukemia algorithm anemia aplastic cll common cvid hemophagocytic hlh hypogammaglobulinemia immunodeficiency immunology lupus lymphocytic lymphohistiocytosis macrophage
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Acquired von Willebrand ... Syndrome - Diagnosis ... and Management ... adsorption onto cancer ... #treatment #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hematologic: Acute blood ... Rebound effect from treatment ... • Infections: Chronic ... Diagnosis #Algorithm #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Non-autoimmune rheumatologic ... with Lupus: • Chronic ... B-cell activation ... • Cervical cancer
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... the secondary or acquired ... Treatment: • Corticosteroids ... #Management #Hematology ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... Purtilo (XLP) Acquired ... B-LNH), solid cancers ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Autoimmunity • Chronic ... Lymphoma or other cancers ... gastric and breast cancer ... severe community-acquired ... hypogammaglobulinemia #immunology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... Hepatomegaly • Skin ... Lymphocytosis: Absolute blood ... microglobulin Treatment ... workup #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... Marrow Failure • Chronic ... factor (GCSF) treatments ... marrow studies Treatment ... #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... • Tumor lysis syndrome ... lymphoid organs When Cancer ... CLL -> Invade Skin ... #Leukemia #Hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
a rare chronic ... and lower jaw Treatment ... #Rheumatology # ... diagnosis #management ... #Dermatology
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