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diagnosis hematology oncology leukemia algorithm aplastic cll common cvid differential immunodeficiency immunology lymphocytic mds myelodysplasia myelodysplastic platelets syndromes thrombocytosis variable
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hematologic: Acute blood ... hemolysis, deficiency anemia ... • Infections: Chronic ... Diagnosis #Algorithm #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Autoimmunity • Chronic ... Lymphoma or other cancers ... gastric and breast cancer ... autoimmune hemolytic anemia ... #immunology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... Hepatomegaly • Skin ... • Neutropenia, anemia ... microglobulin Treatment ... workup #oncology #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin ... Treatment: ... result from low blood ... #oncology #hematology ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... Marrow Failure • Chronic ... factor (GCSF) treatments ... marrow studies Treatment ... #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
- infiltrates (anemia ... lymphoid organs When Cancer ... CLL -> Invade Skin ... Agranulocytosis • Hypogammaglobulinemia ... #Leukemia #Hematology
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