6 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Sjögrens (15%) Skin ... Endocarditis, Aortic ... #signs #symptoms ... #diagnosis #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... syndrome (Clinical ... disease) Differential ... diagnosis #management #signs ... #symptoms #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: erythematous nodules ... VASCULITIS: • Behçet ... Presentation - Systemic Symptoms ... purpura: strong sign ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... < 30 years • Aorta ... : Erythematous nodules ... vasculitis • Behcet ... #Diagnosis #Rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
those coming off aorta ... Diagnosis = clinical ... systemic sx + signs ... required due to skip ... GCA #Temporal #Signs
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
) • Anti-Mi2 (skin ... • Anti-TIF1 (cancer-associated ... papules and Gottron sign ... ) • Shawl sign ... Pericarditis/Pericardial tamponade