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diagnosis differential hematology management infections leukemia oncology algorithm autoimmune chronic cll disorders erythematosus fungal lupus lymphocytic lymphomas lymphoproliferative mycobacteria mycoses
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
pattern of spread, B symptoms ... Amy Chung, MD, MSc ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #Hematology #Diagnosis
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... nodes: 13-15%, skin ... anterior/posterior MSK ... : (distinct symptoms ... ) • Löfgren syndrome
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Lady Windermere Syndrome ... : • Syndrome of ... disease, alcohol, cancer ... • Clinical (Symptoms ... differential #diagnosis #infectiousdiseases
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Disease Classification ... Non-autoimmune rheumatologic ... Induced Lupus: • Symptoms ... • Cervical cancer
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... • Tumor lysis syndrome ... lymphoid organs When Cancer ... CLL -> Invade Skin ... #Leukemia #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... with no early symptoms ... Hepatomegaly • Skin ... • Richter’s Syndrome ... leukemia • Sezary syndrome
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
VASCULITIS: • Behçet Syndrome ... • Cogan Syndrome ... Presentation - Systemic Symptoms ... differential #diagnosis #rheumatology ... #classification
Syphilis - Clinical Manifestations and Treatment 1) Primary Syphilis • Direct lesion contact during sex is responsible
months after the chancre ... weight loss • Skin ... Albuminuria, nephrotic syndrome ... ulcerated • MSK ... infected without symptoms
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... symptoms • Anti-CADM ... ) • Anti-Mi2 (skin ... • Anti-TIF1 (cancer-associated ... Myositis #Myopathy #rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
• Rheumatologic ... osteomyelitis or skin ... Aspergillosis Pathophysiology ... Mouth, throat, skin ... ) #Mycoses #InfectiousDiseases
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