9 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Cerebrovascular Disease ... #rheumatology # ... #management #treatment
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
disease) Differential ... Arthritis, AS Treatment ... #Syndrome #diagnosis ... #management #signs ... #symptoms #rheumatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Immunohistochemical studies (to differentiate ... number of sites of disease ... Lymphoma Treatment ... classification #hematology ... #oncology #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... and CNS • Headache ... cyclophosphamide) • Hodgkin ... #Diagnosis #Rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Systemic lupus erythematosus ... nervous system (CNS ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Nephrogenic DI Hematologic ... Malignancy Risk: • Non-Hodgkins ... Adenocarcinoma Treatment ... #Rheumatology # ... Diagnosis #Management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... ischemia • Skin: Erythematous ... vasculitis • Behcet ... chorioretinitis, CNS ... #Diagnosis #Rheumatology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
systemic lupus erythematosus ... Histopathological Diagnoses ... Hypoalbuminemia Treatment ... agonists #TAFRO #diagnosis ... #management #rheumatology