32 results
Achilles Tendon Rupture in Slow Motion

Caused by high speed knee extension with ankle dorsiflexion.

Dr. Boris Gojanovic
Slow Motion Caused ... Tendon #Rupture #SlowMotion ... #clinical #Video ... #Sports #Mechanism
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
a Sickle Cell Crisis ... Crises can be precipitated ... The underlying pathophysiology ... 4 different mechanism ... of the baseline anaemia
Chorea - Slow Motion 
Chorea is a hyperkinetic movement disorder characterized by unpredictable dancing movements. We
paraneoplastic, toxic causes ... Chorea #neurology #clinical ... video #movements #choreiform ... #slowmotion
Alexia Without Agraphia
Alexia without agraphia is a disconnection syndrome where patients cannot read but can write.
the most common cause ... lobe is unable to cross ... Pathophysiology: ... angular gyrus Clinical ... #Agraphia #clinical
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Pathogenesis and Clinical ... enzyme 21-OHase causes ... • Salt wasting crisis ... "salt wasting crisis ... #21HydroxylaseDeficiency #21OHD #pathophysiology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... pancytopenia Mechanisms ... Clinical Presentation ... and petechiae Causes
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
reticularis Blood: Anemia ... inflammation tends to cause ... pulmonary fibrosis (mechanism ... RheumatoidArthritis #RA #pathophysiology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... blood donor • Pathophysiology ... : 2 hit mechanism ... without other cause ... transfusion • Pathophysiology
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
- Pathophysiology ... the Journal of Clinical ... reasoning during clinical ... Hospitalization: Mechanisms ... #pathophysiology
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
Inhibited Pathway caused ... use of N2O can cause ... The classic clinical ... of pernicious anemia ... #Pathophysiology