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diagnosis management differential neurology hematology nutrition acidosis aplastic ascorbicacid barre cirrhosis classification comparison elevation encephalopathy gbs guillain hemeonc hemophagocytic hepatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
pancytopenia Mechanisms ... Clinical Presentation ... and petechiae Causes ... Treatment: ... • Improve the symptoms
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Risk factors: Critical ... : 2 hit mechanism ... without other cause ... ARDS to explain symptoms ... : 33% • Treatment
Refeeding Syndrome Overview What Is It? • Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
changes and may cause ... severe clinical ... overload) Other Symptoms ... hyperparathyroidism Treatment ... Differential #Diagnosis #Pathophysiology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Management Summary Causes ... Dermatomyositis Clinical ... : • Triad of symptoms ... urine • Other symptoms ... myoglobin AKI Mechanism
Scurvy (Vitamin C Deficiency) - Diagnosis and Management Vitamin C is required for hydroxylation of proline residues
poor nutrition Clinical ... Psychiatric symptoms ... Loss of teeth Anemia ... , or any other cause ... vasculitis Treatment
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
ischemia or the mechanism ... perfusion - shock->treatments ... before beginning treatment ... - Compartment syndrome ... 30mmHg) - Severe anemia
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Etiology: • Pathophysiology ... Neurological symptoms ... the underlying cause ... • Treatment of ... with AEDs until cause
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Prevalence: 1-2 cases ... and pernicious anemia ... Pathophysiology ... Clinical Manifestations ... Treatment: •
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... than one after symptom ... the underlying pathophysiology ... and cauda equina TREATMENT
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... tissue damage Mechanisms ... Transverse Myelitis - Clinical ... Bilateral signs and/or symptoms ... • Infectious causes
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