8 results
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
linear red "Auer rod ... Clinical #Path #BloodSmear ... #Blood #Smear # ... Microscopy #Auer #Rods ... #AuerRods #AML
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
her peripheral blood ... smear showed hypogranular ... Clinical #Path #BloodSmear ... #Blood #Smear # ... #AuerRods #APL
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia (blood ... granules, and Auer rods ... features in most cases ... promyelocytic #leukemia #APL ... Hematology #Clinical #Smear
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... smear or on bone ... : Blast crises ... 50-60 • Auer Rods ... • Peripheral smear
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
plateletcount), peripheral blood ... smear, HIV/HCV ... (CVID, WAS), (neurologic ... not required in all ... dysplasia on the smear
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... deficiency • blood ... collection with EDTA Pathophysiology ... respiratory failure • Neurologic ... Phosphatase: • Other causes
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... thrombosis and/or blood-brain ... (for secondary APS ... Erythematosus #SLE #CNS #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Incidence: 1 to 2 cases ... complete paralysis of all ... normal CSF white blood ... the underlying pathophysiology ... diagnosis #management #neurology