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neurology diagnosis differential causes management acetylcholinereceptor algorithm clinical diplopia eyelid intravenousimmunoglobulin ivig musclespecificreceptortyrosinekinase musk myastheniagravis myastheniccrisis nif ocular ocularmyasthenia ophthalmology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Myasthenia Gravis ... the postsynaptic neuromuscular ... Ab to AChR blocks ... chewing, loss of smile ... Labs: - AchR antibodies
Drugs associated with worsening of Myasthenia Gravis (MG): • D-penicillamine • Botulinum toxin. • Telithromycin • Fluoroquinolones • Quinine • Magnesium • Macrolide antibiotics • Corticosteroids (may cause transient
with worsening of Myasthenia ... Gravis (MG): • ... of generalized AChR-MG ... because of bulbar weakness ... muscle-specificreceptortyrosinekinase #AChR
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm No Objective Weakness • Cardio-pulmonary disease
• Cardio-pulmonary ... Muscular Atrophy Neuromuscular ... Oculomotor • Myasthenia ... Gravis • Lambert-Eaton ... Myasthenic Syndrome
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Weakness • Spinal ... Demyelinating Disease (MS ... Eaton Syndrome, Myasthenia ... Gravis, Organophosphate ... #Weakness #Causes
Ocular Myasthenia Gravis on Physical Exam A 41yo female was referred by her neurologist for double vision.
non-localized EOM weakness ... Myasthenia gravis ... suspected and anti-ACh ... tumor, and always ask ... #clinical #video
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 Myasthenia Gravis - Summary • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Myasthenia Gravis ... the postsynaptic neuromuscular ... or respiratory weakness ... or generalized weakness ... #Gravis #diagnosis
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
: • Non-neuromuscular ... disorder (Cardiac ... Neuromuscular Junction ... Postsynaptic: Myasthenia ... Gravis - Lack
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