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clinical video physicalexam msk orthopedics sports neurology test diagnosis differential injury causes gravis shoulder acl leg management rheumatology sign acetylcholinereceptor
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Myasthenia Gravis ... variable degree of weakness ... chewing, loss of smile ... Limb- proximal weakness ... immunologic assay - MuSK
Drugs associated with worsening of Myasthenia Gravis (MG): • D-penicillamine • Botulinum toxin. • Telithromycin • Fluoroquinolones • Quinine • Magnesium • Macrolide antibiotics • Corticosteroids (may cause transient
with worsening of Myasthenia ... Gravis (MG): • ... higher risk of myasthenic ... because of bulbar weakness ... #VC #NIF #PEF #
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm No Objective Weakness • Cardio-pulmonary disease
of Peripheral Weakness ... • Cardio-pulmonary ... Oculomotor • Myasthenia ... Gravis • Lambert-Eaton ... Myasthenic Syndrome
Ocular Myasthenia Gravis on Physical Exam A 41yo female was referred by her neurologist for double vision.
Ocular Myasthenia ... non-localized EOM weakness ... Myasthenia gravis ... tumor, and always ask ... #clinical #video
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 Myasthenia Gravis - Summary • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Myasthenia Gravis ... or respiratory weakness ... mild to moderate weakness ... or generalized weakness ... #Gravis #diagnosis
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Demyelinating Disease (MS ... Eaton Syndrome, Myasthenia ... Gravis, Organophosphate ... Neuromuscular #Weakness
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... Approach To Weakness ... Non-neuromuscular disorder (Cardiac ... Postsynaptic: Myasthenia ... Gravis - Lack
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
irregularities • Weakness ... diffuse goiter (Graves ... antibodies (TRAb) if ... Graves' disease ... Cardiac arrhythmia
Hydroxychloroquine - Risks and Benefits in Lupus Benefits: ↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
QT) [very rare if ... abnormalities and/or cardiac ... other diseases: myasthenia ... gravis [use with
Froment’s Test for Ulnar Nerve Palsy This tests for pinch grip weakness caused by ulnar nerve palsy,
for pinch grip weakness ... is neuropathy if ... Palsy #clinical #video ... #physicalexam #msk
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