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neurology differential causes gravis management acetylcholinereceptor achr algorithm clinical diplopia endocrinology eyelid hyperthyroidism intravenousimmunoglobulin ivig musclespecificreceptortyrosinekinase musk myastheniagravis myastheniccrisis neuromuscular
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Myasthenia Gravis ... chewing, loss of smile ... Diagnosis - ... immunologic assay - MuSK ... #Gravis #diagnosis
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm No Objective Weakness • Cardio-pulmonary disease
- Differential Diagnosis ... • Cardio-pulmonary ... Oculomotor • Myasthenia ... Gravis • Lambert-Eaton ... Myasthenic Syndrome
Drugs associated with worsening of Myasthenia Gravis (MG): • D-penicillamine • Botulinum toxin. • Telithromycin • Fluoroquinolones • Quinine • Magnesium • Macrolide antibiotics • Corticosteroids (may cause transient
with worsening of Myasthenia ... Gravis (MG): • ... higher risk of myasthenic ... because of bulbar weakness ... #VC #NIF #PEF #
Myasthenia Gravis - Summary • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Myasthenia Gravis ... 50 years in men Diagnosis ... or respiratory weakness ... or generalized weakness ... #Gravis #diagnosis
Ocular Myasthenia Gravis on Physical Exam A 41yo female was referred by her neurologist for double vision.
Ocular Myasthenia ... non-localized EOM weakness ... Myasthenia gravis ... tumor, and always ask ... #clinical #video
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 Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Demyelinating Disease (MS ... Eaton Syndrome, Myasthenia ... Gravis, Organophosphate ... #differential #diagnosis
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Diagnosis Framework ... Non-neuromuscular disorder (Cardiac ... Postsynaptic: Myasthenia ... Gravis - Lack ... #Differential #Diagnosis
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
irregularities • Weakness ... diffuse goiter (Graves ... antibodies (TRAb) if ... Graves' disease ... Cardiac arrhythmia
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