8 results
Workup for Hypophosphatemia - Differential Diagnosis Framework
Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia
Measure Urine Fractional Excretion
- Differential ... Glucose, Acute resp. alkalosis ... • Normal or Low ... - Normal or Low ... #Differential #
Cancer agents and Electrolyte Disorders
 • Hypocalcemia: Cisplatin from Low Mg, Cetuximab- due to low Mg
Axitinib,
Cisplatin from Low ... Regorafenib • Hypophosphatemia ... Regorafenib • Hypomaqnesemia ... Trastuzumab • Hyponatremia ... chemotherapy #diagnosis #differential
Hypophosphatemia - Differential Diagnosis Algorithm
Appropriately Low Kidney Phosphate Excretion:
 • Decreased GI Absorption: Chronic Diarrhea, Antacids,
Hypophosphatemia ... - Differential ... Appropriately Low ... Acute Respiratory Alkalosis ... #Differential #
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Causes of Metabolic Alkalosis ... - Differential ... loop/thiazide) • Hypomagnesemia ... MetabolicAlkalosis #NonGap #Nephrology ... #Differential #
Causes of Hypomagnesemia
 • Redistribution: IV glucose, Correction of diabetic ketoacidosis, IV hyperalimentation, Refeeding after starvation,
Causes of Hypomagnesemia ... depletion, Familial hypophosphatemia ... #Causes #differential ... #diagnosis #nephrology ... #magnesium #low
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Metabolic Alkalosis ... • Normal/low ... Gitelman syndrome, Hypomagnesemia ... urine #Algorithm #nephrology ... #differential #
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
hypokalemia, mild hypomagnesemia ... • Metabolic alkalosis ... • Normal or low ... Hypochloremic metabolic alkalosis ... ratio 0.5%) Differential
Citrate Anticoagulation Toxicity

Hypernatremia (HyperNa):
 - Citrate solutions may have ↑ sodium content and should be paired
Anticoagulation Toxicity Hypernatremia ... replacement fluid Hypomagnesemia ... dysfunction or low ... metabolism Metabolic alkalosis ... Toxicity #toxicology #nephrology