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diagnosis rheumatology msk joint workup approach causes cppd monoarticular algorithm blood comparison deposition erythematosus gout hematuria inflammatory jointpain laboratory lupus
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Symptoms of Joint Disease ... Crystal Deposition ... : • Acute or chronic ... ochronosis and crystal ... approach #workup #differential
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
• Underlying disease ... precipitates with calcium ... Acute CPP Crystal ... onset of swelling, pain ... swelling, significant pain
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pseudogout Summary - Calcium ... precipitates with calcium ... Acute CPP Crystal ... onset of swelling, pain ... neck pain, fever
Differential Diagnosis of Acute Arthritis Crystal-induced arthritis: Calcium oxalate, gout, cholesterol, pseudogout, hydroxyapatite crystals Infectious arthritis: Bacteria, fungi,
Differential Diagnosis ... of Acute Arthritis ... Crystal-induced ... arthritis: Calcium ... #Acute #Arthritis
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 Inflammatory Joint Pain - Differential Diagnosis Algorithm Monoarticular • Gout (Podagra, Tophi) • Pseudogout • Early
Inflammatory Joint Pain ... - Differential ... polyangiitis (GPA)/microscopic ... Rheumatic Fever Acute ... JointPain #MSK #Differential
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
Hematuria - Differential ... basement membrane disease ... Post-infectious GN - Loin pain ... syndrome: • Flank pain ... of glomerular disease
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Approach to Joint Pain ... disease, spondyloarthropathies ... Inflammatory, crystalline disease ... #Joint #Pain #MSK ... approach #workup #differential
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
- Arthritis Differential ... the time course (acute ... MONOARTHRITIS • Acute ... Inflammatory • Crystal ... Joint #pain #Differential
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
polarized light microscopy ... (gout) or calcium ... Screening Tests for Acute ... , and low back pain ... • Serum and urine
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... permanent alopecia Differential ... Pleural effusions • Acute ... : • Joint pain ... edema, active urine
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