14 results
Drugs affecting the cardiac action potential. The sharp rise in voltage ("0") corresponds to the influx
Drugs affecting ... to the sodium-channel ... repolarizing eflux of potassium ... #Pathophys #Pharmacology ... Antiarrhythmics #Classes
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
1 - Sodium Channel ... 3 - Potassium Channel ... Vaughan #Williams #Pharmacology ... Classification #Classes ... #pathophysiology
Common sodium channel blockers which cause QRS widening.

Anticonvulsants: 
 - Carbamazepine 
Antidysrhythmics:  
 - Group
Common sodium channel ... blockers which cause ... widening #ECG #EKG #Pharmacology ... Medications #Toxicology #Diagnosis ... #Classes
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... 3 - Potassium Channel ... Antiarrhythmics #Pharmacology ... Classification #Classes ... #pathophysiology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... Heparin) • Sodium-channel ... #pathophysiology ... #pharmacology # ... potassium #medications
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
Causes of Hypomagnesemia ... osmotic diuresis - Potassium ... Hypomagnesemia #Causes ... #diagnosis #differential ... #pharmacology #
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
- Differential Diagnosis ... reactions Common Drugs ... • Recent IV potassium ... Avocados, Lima beans ... #causes #potassium
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
- Differential Diagnosis ... reactions Common Drugs ... • Recent IV potassium ... Avocados, Lima beans ... #causes #potassium
Drug-Induced Urinary Retention

Drug-induced urinary retention is very common and can be caused by many classes of
by many classes ... Classes Causing ... NSAIDs • Calcium channel ... #differential #diagnosis ... #pharmacology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
- Differential Diagnosis ... Drugs (Statins), ... Dermatomyositis) AKI - Pathophysiology ... Monitor potassium ... Management #Summary #causes