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diagnosis differential management algorithm nephrology causes pharmacology cardiology treatment table hypokalemia potassium ekg clinical hypercalcemia endocrinology pathophysiology ecg hyponatremia medications
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... Sodium zirconium ... for hydrogen and sodium ... to moderate); hypokalemia ... • Mechanism: Sodium-K
ECG Changes in Hyperkalemia and Treatment Membrane Stabilization - Calcium gluconate or chloride Redistribution - Insulin
ECG Changes in Hyperkalemia ... Albuterol - Sodium ... Furosemide - Sodium ... Hemodialysis #Hyperkalemia
Hyperkalemia Management Membrane Stabilizers: • Calcium gluconate Shifters: • Insulin + glucose • Albuterol Excreters: • Furosemide • Sodium
Hyperkalemia Management ... Furosemide • Sodium ... bicarbonate • Sodium ... Medicine @ucsdim #Hyperkalemia
Potassium Binders for Management of Hyperkalemia • SPS - Sodium polystyrene sulfonate • Patiromer (veltassa) •
Management of Hyperkalemia ... • SPS - Sodium ... veltassa) • SZC - Sodium ... Binders #Management #Hyperkalemia
Drugs causing hyperkalemia • Impaired release of renin: NSAIDs, Beta blockers, Cyclosporine, tacrolimus, Diabetes, Elderly •
Drugs causing hyperkalemia ... Ketoconazole • Sodium ... Drospirenone #Drugs #hyperkalemia
Acute Hyperkalemia Management • Membrane Stabilization: Calcium Gluconate (10%), Hypertonic (3%) Normal Saline • Shifters: Insulin
Acute Hyperkalemia ... Excreters: Furosemide, Sodium ... Bicarbonate, Sodium ... Hemodialysis #Acute #Hyperkalemia
Causes of Hyperkalemia - Differential Diagnosis Framework • Cellular Shift: - Exercise
Causes of Hyperkalemia ... tacrolimus - Hyperkalemic ... distal tubule sodium ... Hemolysis • Pseudo hyperkalemia ... Medicine @ucsdim #Hyperkalemia
Emergency Therapy of Hyperkalemia Therapy - Dose and Route - Onset of Action - Duration of Effect
Emergency Therapy of Hyperkalemia ... glucose, Furosemide, Sodium ... Hemodialysis #Hyperkalemia
Treatment of Hyperkalemia Membrane Stabilization • Calcium Gluconate (10%) • Hypertonic (3%) Normal Saline Shifters: • Insulin (Short
Treatment of Hyperkalemia ... Furosemide • Sodium ... Bicarbonate • Sodium ... Hemodialysis #Hyperkalemia
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... (Heparin) • Sodium-channel ... MunerMohamed1 #hyperkalemia
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