7 results
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
degranulation, leading ... surfaces causes ... immune reaction, leading ... causes development ... #Types #Classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... lgE causes mast-cell ... antigens, leading ... reactions #types #allergy ... #table #classification
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
rapidly progresses: cell ... death -> end-organ dysfunction ... #Classification ... #differential #causes ... #classification
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
rapidly progresses: cell ... death -> end-organ dysfunction ... #Classification ... #differential #causes ... #classification
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
• 49 million cases ... risk death), T-cell ... COMMON CAUSES + ... all suspected cases ... • Start broad-spectrum
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm
Structural Defect - Asplenia/HypospIenism
 • Bacteremia/Septic
Causes of Fever ... Bacteremia/Septic Shock ... Encapsulated Bacteria Cell ... or Neutrophil Dysfunction ... #Causes #Hematology
Langerhans Cell Histiocytosis (LCH)

Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
various tissues, leading ... populations) CLINICAL SPECTRUM ... • Endocrine Dysfunction ... marrow: Organ dysfunction ... for endocrine dysfunctions