20 results
Hypomagnesemia - Differential Diagnosis
Renal Causes of Hypomagnesemia - Familial:
Bartter syndrome and Gitelman syndrome, Isolated recessive hypomagnesemia,
Familial: Bartter syndrome ... and Gitelman syndrome ... with secondary, hypocalcemia ... #nephrology #magnesium ... #low
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... , mild hypomagnesemia ... • Normal or low ... Hypocalciuria (spot
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
Hypomagnesemia - ... Hypercalcemia - Hypokalemia ... Differential #Diagnosis #Low ... Classification #Causes ... #Workup #hypomg
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... Defining the cause ... starts by measuring ... Renal K loss • Hypomagnesemia-induced ... #nephrology #potassium
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
Hypokalemia ... overdose) - Sodium ... renal Fanconi syndrome ... differential #diagnosis #nephrology ... #Causes #hypomg
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
thiazide-sensitive sodium-chloride ... H+ secretion → Hypokalemia ... Metabolic alkalosis ... Hypermagnesuria, Hypomagnesemia ... Pathophysiology #nephrology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... Transcellular Shifts: - Alkalosis ... Alcoholism (worsened by hypomagnesemia ... #Causes #differential ... #diagnosis #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
wasting from other causes ... suggests extra-renal causes ... consumption • Low ... - Metabolic Alkalosis ... #low
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Causes of Metabolic ... Alkalosis - Differential ... loop/thiazide) • Hypomagnesemia ... Licorice • Liddle's Syndrome ... Diagnosis #Algorithm #Causes
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
• Normal/low ... , Gitelman syndrome ... , Hypomagnesemia ... the indicated causes ... the excretion of sodium