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diagnosis management hematology classification vasculitis antimda5 antimda5dm antinxp2 antinxp2dm arteritis autoimmune common conditions cryofibrinogenemia cvid cxr dermatologic diseases erythematosus extrarticular
Interstitial Lung Diseases (ILD) Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): • Hypersensitivity pneumonitis, Farmer's lung, Bird
Interstitial Lung ... , Polymyositis-dermatomyositis ... Langerhans cell ... ILD #diagnosis #differential ... #pulmonary #causes
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
auricular papules Clinical ... CD4+ and CD8+ T cell ... anti-NXP2 Abs Lung ... #rheumatology # ... dermatology #diagnosis
Differential diagnosis on HRCT Most of our knowledge about imaging findings in interstitial lung disease comes from
Differential diagnosis ... lung disease comes ... in Langerhans cell ... #Diagnosis #Radiology ... #Pulmonary #CXR
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... disease Interstitial ... Langerhans cell ... Classification #Diagnosis #Differential ... #Causes
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... ducts Clinical ... , INC risk PE, Pulmonary ... MALT Lymphoma • Lung ... Sjogrens #Syndrome #Rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... reticularis Differential ... syndrome • Giant cell ... rash #diagnosis #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
• Interstitial ... lung disease - ... Scleroderma Thickened skin ... #joint #pain #differential ... #diagnosis #rheumatology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Advanced HIV (CD4 cell ... Disease: Clinical ... Disease: • Clinical ... NTM #Infections #differential
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
auricular papules Clinical ... Muscle atrophy may cause ... lung carcinoma ... diagnosis #management #rheumatology ... #dermatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
CRP GCA (Giant Cell ... Multinucleated giant cells ... tract, and often causes ... inflammatory lesions - interstitial ... #Diagnosis #Rheumatology
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