15 results
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
ulcerations • Skin ... auricular papules Clinical ... CD4+ and CD8+ T cell ... anti-NXP2 Abs Lung ... #rheumatology #dermatology
Ear Pain (Otalgia) - Differential Diagnosis Framework

Primary Otalgia 
 - Pain that originates from the ear
Cholesteatoma • Basal/squamous ... cell CA • Melanoma ... Inflammatory Causes ... the following symptoms ... subdural hematoma, lung
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Syndromes - Non-inflammatory ... neoplasms (e.g., nasal squamous ... cell carcinoma) ... MRI lesions and clinical ... noninflammatory #differential
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Advanced HIV (CD4 cell ... Disease: Clinical ... (Symptoms, Imaging ... NTM #Infections #differential
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
granulomas within the lungs ... renal failure Clinical ... Pulmonary: dyspnea ... acute sarcoidosis Pulmonary ... nodes: 13-15%, skin
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Presentation: Systemic Symptoms ... • Progressive symptoms ... tract, and often causes ... syndrome: Ocular inflammatory
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Symptoms ... (COVID-19) • Inflammatory ... thrombophlebitis, pulmonary ... occlusions, as well ... cryoglobulins • Negative causes
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... tract, and often causes ... Syndrome: - Ocular inflammatory ... episcleritis as well ... Presentation - Systemic Symptoms
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... ingestion • B symptoms ... or low • ESR (Inflammatory ... and inflammatory ... Immunohistochemical studies (to differentiate
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
auricular papules Clinical ... Muscle atrophy may cause ... carcinoma • Clear cell ... lung carcinoma ... #rheumatology #dermatology