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diagnosis treatment differential tb tuberculosis activetb hematology hivaids idsa latenttb opportunistic prevention anemia aplastic aviumcomplex extravascular hemolysis hemophagocytic hlh inflammatory
Lymphadenopathy - Differential Diagnosis Algorithm Localized: • Cervical: EBV, CMV, HIV, Toxo, TB, Lymphoma, Head /
Differential Diagnosis Algorithm ... Generalized: • Auto-immune ... Acute HIV, EBV, Mycobacterial ... Anti-epileptic drugs ... #Causes
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Differential Diagnosis Algorithm ... Sickle cell • Unstable ... circulation - Infections ... immune-complex
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
that disrupts immune ... ↑ sIL-2R >2400 Ul ... ..), Bacteria (Mycobacteria ... deficiency, Drugs ... Lymphohistiocytosis #diagnosis #management
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
drug use • Silicosis ... Progression: (+) Immune ... rest LTBI (-) Immune ... • Granulomas unable ... TB #Diagnosis #Management
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
drug use • Silicosis ... Progression: (+) Immune ... rest LTBI (-) Immune ... • Granulomas unable ... TB #Diagnosis #Management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
mutations) • Immune ... and petechiae Causes ... - Cytotoxic drugs ... Parvovirus B19 • Mycobacteria ... hematology #diagnosis #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Immune Reconstitution ... • A state of hyperinflammatory ... organizing PNA • Mycobacterium ... unintentional weight loss, nausea ... Differential #Diagnosis #Management
IDSA Recommendations for Preventing and Treating Disseminated Mycobacterium Avium Complex in HIV-AIDS Preventing 1st Episode of Disseminated
Treating Disseminated Mycobacterium ... please refer to Table ... Prevention #Treatment #management ... opportunistic #infections ... #HIVAIDS #pharmacology
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS Treating LTBI (to prevent TB disease) Indications:
Recommendations for Treating Mycobacterium ... Please refer to the table ... #LTBI #Mycobacterium ... Prevention #Treatment #management ... #HIVAIDS #pharmacology
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