9 results
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
drug use • Silicosis ... • Granulomas unable ... Tuberculosis Treatment ... #Diagnosis #Management ... #Treatment #ActiveTB
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
drug use • Silicosis ... • Granulomas unable ... Tuberculosis Treatment ... #Diagnosis #Management ... #Treatment #ActiveTB
IDSA - Clinical Strategy to Build an Individualized Treatment Regimen for Multi-Drug Resistant Tuberculosis (MDR-TB)
 •
Individualized Treatment ... are contacts of infectious ... MDR-TB source cases ... Tuberculosis #MDRTB #management ... #regimens #pharmacology
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS
Treating LTBI (to prevent TB disease)
Indications:
Recommendations for Treating Mycobacterium ... below for TB drug ... #LTBI #Mycobacterium ... #management #opportunistic ... #pharmacology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
↑ sIL-2R >2400 Ul ... ..), Bacteria (Mycobacteria ... immune deficiency, Drugs ... , Unknown cause ... Lymphohistiocytosis #diagnosis #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... - Cytotoxic drugs ... Parvovirus B19 • Mycobacteria ... Treatment: ... hematology #diagnosis #management
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
polymicrobial infection ... • Most common cause ... Leukocytosis, anemia ... westermani • Other: TB ... #management #treatment
IDSA Recommendations for Preventing and Treating Disseminated Mycobacterium Avium Complex in HIV-AIDS
Preventing 1st Episode of Disseminated
Note: Active TB ... IDSA #Prevention #Treatment ... #management #opportunistic ... #infections #HIVAIDS ... #pharmacology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
• A state of hyperinflammatory ... organizing PNA • Mycobacterium ... unintentional weight loss, nausea ... /drug resistance ... Differential #Diagnosis #Management