8 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
↑ sIL-2R >2400 Ul ... CMV, HHV8,...), Bacteria ... immune deficiency, Drugs ... Treatment: • Etiological ... diagnosis #management #treatment
Antibiotic classification refers to the categorization of antibiotics based on their chemical structure, mechanism of action,
Antibiotics are drugs ... treat bacterial infections ... Imagine treatments ... #Antibiotics #pharmacology ... classification #table
IDSA Recommendations for Preventing and Treating Histoplasma Capsulatum Infections in HIV-AIDS
Indications for Initiating Primary Prophylaxis:
 •
Infections in HIV-AIDS ... histoplasmosis (>10 cases ... with ARV (see Table ... IDSA #Prevention #Treatment ... #HIVAIDS #pharmacology
IDSA Recommendations for Treating Cytomegalovirus Infections in HIV-AIDS
Preventing CMV Disease:
 • CMV end-organ disease is best
Cytomegalovirus Infections ... intraocular levels of drug ... control of the infection ... until steady state ... #HIVAIDS #pharmacology
Sulfonamides - Antibiotics Class Overview

BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic

Spectrum: Wide
Class Overview BACTRIM ... Notable highlights ... including PCP PNA (drug ... choice, both for treatment ... #Pharmacology #Antibiotics
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
• A state of hyperinflammatory ... superinfection, drug ... unintentional weight loss, nausea ... • Histoplasma capsulatum ... /drug resistance
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS
Treating LTBI (to prevent TB disease)
Indications:
Mycobacterium Tuberculosis Infection ... a person with infectious ... Please refer to the table ... opportunistic #infections ... #HIVAIDS #pharmacology
IDSA Recommendations for Preventing and Treating Disseminated Mycobacterium Avium Complex in HIV-AIDS
Preventing 1st Episode of Disseminated
necessary based on drug-drug ... please refer to Table ... IDSA #Prevention #Treatment ... opportunistic #infections ... #HIVAIDS #pharmacology