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management differential idsa opportunistic prevention summary mycobacterium rhabdomyolysis abscess algorithm anemia aplastic aviumcomplex capsulatum cheatsheet comparison coronavirus covid19 criticalcare cytomegalovirus
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
↑ sIL-2R >2400 Ul ... +: Virus (EBV, CMV ... or biologics (CMV ... immune deficiency, Drugs ... , Unknown cause
Important causes of diarrhea in people with HIV/AIDS Severity, chronicity/persistence will depend On CD4 count & sites
count & sites of infection ... 2) Viral: - CMV ... insufficiency, drug-induced ... #Diarrhea #HIVAIDS ... #Differential #Diagnosis
IDSA Recommendations for Treating Cytomegalovirus Infections in HIV-AIDS Preventing CMV Disease: • CMV end-organ disease is best
Cytomegalovirus Infections ... intraocular levels of drug ... control of the infection ... until steady state ... #HIVAIDS #pharmacology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... /HDS treatments ... for alternative causes ... Hepatocellular: Viral infections ... HCV, HEV, EBV, CMV
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... - Cytotoxic drugs ... - EBV - CMV ... aplastic anemia Treatment ... oncology #hematology #diagnosis
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
- Differential Diagnosis ... Drugs (Statins), ... ETOH Infection ... per day until stable ... Management #Summary #causes
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
polymicrobial infection ... • Most common cause ... antibiotics once stable ... Cavitation > 6 cm ... shows a small, stable
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
• A state of hyperinflammatory ... superinfection, drug ... keratitis, iritis • CMV ... unintentional weight loss, nausea ... /drug resistance
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... Management Summary Causes ... - Toxins - Drugs ... Statins - ETOH - Infection ... per day until stable
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS Treating LTBI (to prevent TB disease) Indications:
Mycobacterium Tuberculosis Infection ... a person with infectious ... and molecular diagnostic ... Please refer to the table ... #HIVAIDS #pharmacology
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