131 results
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
Basement Membrane (GBM ... staining on IF ... • No EM deposits ... cytoplasmic neutrophilic staining ... perinuclear cytoplasmic staining
Goal-Directed Therapy - Evidence Summary of Major Clinical Trials

 - EGDT: NEJM 2001

 - ProCESS: NEJM
Trials - EGDT: NEJM ... - ProCESS: NEJM ... 2014 - ARISE: NEJM ... - ProMlSe: NEJM ... Therapy #Trials #EBM
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Mediated (granular staining ... Henoch-SchonIein Purpura Anti-GBM ... antibodies (linear staining ... to Kidney: Anti-GBM ... involvement: Anti-GBM
PCI in Acute MI with Cardiogenic Shock. #EBM #Cardiology #CULPRITSHOCK #PCI #VisualAbstract #NEJM
#EBM #Cardiology ... VisualAbstract #NEJM
Tinea Versicolor - Physical examination revealed large, coalescing, hypopigmented patches and macules on her torso and
Melan-A staining ... periodic acid–Schiff staining ... Microscopy #Spaghetti #NEJM
A Controlled Trial of Erenumab for Episodic Migraine #EBM #Neuro #Erenumab #Migraine #CGRP #VisualAbstract #NEJM
Episodic Migraine #EBM ... VisualAbstract #NEJM
Trial of Solanezumab for Mild Dementia Due to Alzheimers Disease #EBM #Dementia #Solanezumab #Alzheimers #NegativeTrial #VisualAbstract
Alzheimers Disease #EBM ... VisualAbstract #NEJM
Macroglossia in Light-Chain Amyloidosis- Physical examination revealed macroglossia, with indentations from the teeth (Panel A)...A biopsy
after Congo red staining ... amyloidosis #clinical #photo ... AL #lightchain #NEJM
Glecaprevir and Pibrentasvir in Patients with HCV and Severe Renal Impairment #EBM #Hepatology #HCV #CKD #Glecaprevir
Renal Impairment #EBM ... VisualAbstract #NEJM
An AAV5 vector with a functional factor VIII gene tested in men with hemophilia A #EBM
hemophilia A #EBM ... VisualAbstract #NEJM