4 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
in 1923 Low ALP ... nephrocalcinosis • CPPD ... Wilson's disease • hypothyroidism ... collection with EDTA Pathophysiology ... , ↓ALPLow
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
Hyperthyroidism ... Manifestation of Hyperthyroidism ... Diagnosis: • ↓ Low ... Size Thyroid Storm ... Hyperglycemia - ↑ AST/ALT
Hypophosphatemia and Hypoxia - Pathophysiology

↓ Phosphate leads to ↓ red cell 2,3-DPG and a  reduction
and Hypoxia - Pathophysiology ... weakness (defined as low ... inspiratory pressure or low ... patients with COPD ... respiratory #hypoxia #pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
• In all patients ... Pathophysiology ... • Cytokine storm ... Low/absent NK-cell