8 results
Hypothyroidism and Hyperthyroidism - Symptoms and Signs
Hypothyroidism:
 - General - From asymptomatic to myxedema coma, “Like
Hypothyroidism and ... Hyperthyroidism ... down” • Low ... - GI • Constipation ... running a marathon all
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
in 1923 Low ALP ... nephrocalcinosis • CPPD ... Wilson's disease • hypothyroidism ... collection with EDTA Pathophysiology ... , ↓ALPLow
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
Hyperthyroidism ... Manifestation of Hyperthyroidism ... Diagnosis: • ↓ Low ... Size Thyroid Storm ... Hyperglycemia - ↑ AST/ALT
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
weight loss - Low ... disturbances: low ... PO4 -> decr RBC ATP ... GI: Anorexia, Constipation ... Syndrome #diagnosis #pathophysiology
Hypophosphatemia and Hypoxia - Pathophysiology

↓ Phosphate leads to ↓ red cell 2,3-DPG and a  reduction
and Hypoxia - Pathophysiology ... weakness (defined as low ... inspiratory pressure or low ... patients with COPD ... respiratory #hypoxia #pathophysiology
Pathogenesis of Select Causes of Constipation in Adults and in Elderly

 • Mechanical (ex. Bowel Obstruction,
Select Causes of Constipation ... -> Interrupted flow ... Hypothyroidism) ... transit time #constipation ... #pathophysiology
Anorexia Nervosa: Complications
CARDIAC ABNORMALITIES
 - Functional: Low BP, Sinus bradycardia, prolonged QT interval
 - Structural: Reduced
- Functional: Low ... Gastroparesis and Constipation ... T4 - Females: Low ... mortality rates of all ... Complications #pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
• In all patients ... Pathophysiology ... • Cytokine storm ... Low/absent NK-cell