9 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs ... Spheroid mass in vitreous ... detachment • Red Eye ... Secondary glaucoma • Strabismus ... ophthalmology #diagnosis #signs
Diplopia - Double Vision - Differential Diagnosis Algorithm
Clinical Pearls:
 • Diplopia is almost always binocular.
 •
Double Vision - Differential ... • Examine both eyes ... • Neurologic ... Distortion/Scarring • Vitreous ... #DoubleVision #Differential
44M with h/o DM2 and insulin noncompliance presents w R eye visual loss x 3d. What's
noncompliance presents w R eye ... washing machine" sign ... on eye movement ... #Clinical #POCUS ... WashingMachine #Sign
Cytomegalovirus (CMV) in HIV-AIDS Patients
Cytomegalovirus (CMV): double-stranded DNA virus, herpesvirus family.
CMV infection: virus isolation or detection
of symptoms or signs ... 50 or less: • Neurologic ... Neuropathy • Eye ... AIDS #diagnosis #differential ... #signs #symptoms
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
consciousness Differential ... Test downward eye ... coma Abnormal Eye ... • Examine for signs ... #PhysicalExam #neurology
13 Dangerous Causes of Headache:
 - subarachnoid hemorrhage: family history, PCKD, known berry aneurysm, sudden and
in vision, red eye ... thrombophilia, neurologic ... signs/symptoms ... Dangerous #Deadly #Differential
Photophobia and Headache - Differential Diagnosis Framework

Why?
• The coexistence of photophobia and headache suggests the potential
and Headache - Differential ... meningeal irritation signs ... Disorder of the eyes ... Photophobia #Headache #differential ... ophthalmology #Neurology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
: Inflammatory eye ... skin injury) • Neurologic ... Genital ulcers • Eye ... Behcet disease) Differential ... diagnosis #management #signs
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Arthralgias • Eye ... purpura: Strong sign ... affects the skin, neurologic ... cognitive impairment, neurologic