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diagnosis apml differentiation evaluation hematology management nonpalpable oncology perioperative petechiae petechial preop purpural purpuric rash syndrome
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
Preoperative Risk ... or family - Ever ... event, follow ACC algorithm ... CARP, DECREASE V trials ... #stratification
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH These rashes can be especially challenging and are associated with devastating differential
petechiae/purpura with fever ... petechiae/purpura with fever ... the patient is afebrile ... require complete assessment ... #Diagnosis #Dermatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Attempt if high risk ... Subacute-Acute: • Common: fever ... Rare: DAH, acute febrile ... initiation • Differential ... diagnosis #management #hematology
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