8 results
Diagnosing Vitamin B12 and/or Folate Deficiency

It turns out that simply measuring serum levels of B12 or
stores have normal ... tissue stores. ... deficiency. ... tissue folate stores ... Diagnosis #Nutrition #Hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... mevalonate kinase deficiency ... Prunelle Getten #AdultOnset ... Disease #diagnosis #management ... #treatment #rheumatology
Etiologies of Folate Deficiency
 • Decreased dietary intake - uncommon in this era
 • Increased requirements
Etiologies of Folate Deficiency ... mobilize folate stores ... depleted tissue stores ... #FolicAcid #differential ... #diagnosis #hematology
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Allopecia - Differential ... Lithium • Stress ... texture at bald spots ... loss #alopecia #Differential ... #Diagnosis #dermatology
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
Receptor (sTfR) to differentiate ... (B12, MMA) for ... restricted diet/deficiency ... active IBD and/or stress ... Algorithm #diagnosis #management
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... : • Vit B12 - aka ... large total body stores ... #Cobalamin #Deficiency ... #diagnosis #management
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Pinpoint-sized red spots ... Nutritional: vitamin B12 ... or folic acid deficiency ... blood count with differential ... Syndromes #diagnosis #hematology
Management of Pruritus in Patients with Chronic Kidney Disease
Pruritus with no primary lesions - differential diagnosis:
Management of Pruritus ... primary lesions - differential ... pruritus • Hematologic ... pruritus (Iron deficiency ... Keep fingernails short