33 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Complement: Post-strep ... With associated pulmonary ... diagnosis #algorithm #rheumatology
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework

High Altitude Pulmonary Edema:
 • Accumulation
- Dyspnea at rest ... epilepticus • Pathophysiology ... Edema: • Pathophysiology ... The predominant pathophysiologic ... • Pathophysiology
Diagnosing Vitamin B12 and/or Folate Deficiency

It turns out that simply measuring serum levels of B12 or
with low B12 stores ... normal tissue stores ... the first line tests ... tissue folate stores ... Diagnosis #Nutrition #Hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... without other cause ... transfusion • Pathophysiology ... of (Acute resp distress ... , and CXR with pulmonary
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework

NCPE Pathophysiology:
Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
Noncardiogenic Pulmonary ... Framework NCPE Pathophysiology ... Noncardiogenic pulmonary ... Causes include: ... Acute respiratory distress
Iron Deficiency Anemia (IDA)
Tests:
 • MCV/RBC - RBC ↓ in proportion to the ↓ in hemoglobin
Anemia (IDA) Tests ... total body iron stores ... Fe #diagnosis #hematology
Posterior Cruciate Ligament (PCL) Injury: Pathogenesis and Clinical Findings
Classification of PCL Iniuries
 • Partial: Translation <
Some sort of end ... Varus & Valgus Stress ... Varus & Valgus Stress ... #Injury #MSK #Sports ... #pathophysiology
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Lithium • Stress ... disease • Pull test ... Scaling, pustules, crusts ... texture at bald spots ... Initial Laboratory Tests
Etiologies of Folate Deficiency
 • Decreased dietary intake - uncommon in this era
 • Increased requirements
folate that can cause ... mobilize folate stores ... depleted tissue stores ... differential #diagnosis #hematology
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
over areas of stress ... inflammation tends to cause ... interstitial lung disease/pulmonary ... RheumatoidArthritis #RA #pathophysiology