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diagnosis differential clinical dermatology diseases drugreaction skinrash ucsdh management algorithm amiodarone boop comparison cryptogenic eosinophilic induced interstitial legs mnemonic organizing
Eosinophilia - Differential Diagnosis Algorithm Idiopathic Eosinophilia Primary Eosinophilia: • Primary hypereosinophilic syndrome • Eosinophilic Leukemia • MPN/MDS
GI, lung, skin), ... histiocytosis • Allergic ... Hypersensitivity (DRESS ... IBD Stanford Internal ... Diagnosis #Algorithm #allergy
Interstitial Lung Diseases (ILD) Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): • Hypersensitivity pneumonitis, Farmer's lung, Bird
a.k.a. extrinsic allergic ... ILD caused by inhalation ... organizing pneumonia (COP ... Churg Strauss syndrome ... #causes
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS represents
Systemic Signs (DRESS ... hypersensitivity reaction, DRESS ... associated with allergic ... Dermatology #SkinRash #DRESS ... #Photo #UCSDH
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS represents
Systemic Signs (DRESS ... hypersensitivity reaction, DRESS ... associated with allergic ... Dermatology #SkinRash #DRESS ... Legs #Photo #UCSDH
Differential Diagnosis of Pulmonary Eosinophilia Infection: • Helminthic: Loffler syndrome (Ascaris, hookworm, Strongyloides), Tropical pulmonary eosinophilia (lymphatic
Helminthic: Loffler syndrome ... coccidioidomycosis), Allergic ... polyangiitis (EGPA, Churg-Strauss ... Washington University ID ... #Diagnosis #causes
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS represents
Systemic Signs (DRESS ... hypersensitivity reaction, DRESS ... associated with allergic ... Dermatology #SkinRash #DRESS ... Trunk #Photo #UCSDH
Approach to Eosinophilic Lung Diseases • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
Lung Diseases ... loss, malaise • Allergic ... Hypereosinophilic Syndrome ... similar to AEP or CEP ... #pulmonary #differential
Cryptogenic Organizing Pneumonia (COP) Cryptogenic Organizing Pneumonia Overview: • Idiopathic form of organizing pneumonia • formerly BOOP
Unknown • 6-7 cases ... studies legionella/strep ... pneumonia, Chronic eosinophilia ... #BOOP #pulmonary ... #ILD #diagnosis
Upper Lobe Lung Diseases - STAR CHASERS Mnemonic S - Silicosis T - Tuberculosis A - Ankylosing Spondylitis R -
Sarcoidosis E - Eosinophilic ... Therefore, conditions caused ... elimination of CO2 ... • ↑ Mechanical stress ... pneumonitis - Allergic
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
rarely present with eosinophilic ... acute respiratory distress ... syndrome) is rare ... Exclusion of other ILDs ... LDH • ↑ ESR, CRP
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