8 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Syndrome is a rare ... H+ secretion → Hypokalemia ... Metabolic alkalosis ... #nephrology #diagnosis
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... cotransporter • Gitelman's ... hypomagnesemia • Metabolic alkalosis ... Hypochloremic metabolic alkalosis ... #nephrology #management
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation ... Before evaluating hypokalemia ... - Metabolic Alkalosis ... , Gitelman syndrome ... differential #potassium #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Diagnosis Algorithm Hypovolemia ... and metabolic alkalosis ... Hypovolemia, UNa ... Hypothyroidism, Stress ... Algorithm #Causes #nephrology
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Interpretation Steps ... ABG And BMP Normal ... D-lactate (short bowel syndrome ... Classically” noted with pulmonary ... Diagnosis #Summary #Nephrology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Transcellular Shifts: - Alkalosis ... diuresis, Bartter's syndrome ... diuretic use), Gitelman's ... syndrome (mimics ... differential #diagnosis #nephrology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... testing: anti-ANCA ab ... , anti-GBM ab, ANA ... , biopsy By Tess ... differential #diagnosis #nephrology
Gitelman Syndrome - Diagnosis and Workup
Blood Work:
 - Hypokalemia
 - Hypomagnesemia
 - Metabolic Alkalosis
 - Elevated
Gitelman Syndrome ... Blood Work: - Hypokalemia ... Hypomagnesemia - Metabolic Alkalosis ... #Syndrome #Diagnosis ... #Workup #nephrology