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Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework

NCPE Pathophysiology:
Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
Diagnosis Framework NCPE ... Causes include: ... respiratory distress ... syndrome (ARDS) ... lung injury (TRALI
Acute Respiratory Distress Syndrome – ARDS: Clinical Cheat Sheet

An acute diffuse, inflammatory lung injury, leading to
Distress Syndrome ... , inflammatory lung ... leading to increased pulmonary ... consistent with pulmonary ... RespiratoryDistress #Syndrome
Effect of Lung Recruitment and Titrated Positive End-Expiratory Pressure (PEEP) vs Low PEEP on Mortality in
Patients With Acute ... Respiratory Distress ... Syndrome JAMA ... increased 28-day all-cause ... Postoperative #Pulmonary
Abnormalities in Rate and Rhythm of Breathing 
Normal 
The respiratory rate is about 14—20 per min
Sighing Respiration ... hyperventilation syndrome—a ... In lung disease ... #Pulmonary #Abnormalities ... Abnormal #Diagnosis #PhysicalExam
Pulmonary Pathology and Associated Lung Ultrasound Findings
Pneumothorax:
 - No lung sliding/barcode sign
 - Lung point (hard
Pulmonary Pathology ... pleura in severe cases ... the severity Acute ... Respiratory Distress ... Syndrome (ARDS)
Berlin Criteria for Acute Respiratory Distress Syndrome (ARDS) 
- Respiratory symptoms must have begun within one
Berlin Criteria for Acute ... Syndrome (ARDS) ... consistent with pulmonary ... lobar collapse, lung ... #Distress #Syndrome
Interstitial Lung Diseases (ILD)
Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): 
 • Hypersensitivity pneumonitis, Farmer's lung, Bird
ILD caused by inhalation ... pneumonia (DIP), Acute ... Churg Strauss syndrome ... Eosinophilic pneumonia: Acute ... #causes
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework

High Altitude Pulmonary Edema:
 • Accumulation
Edema (NCPE) - ... blood cells in the lung ... of acute respiratory ... failure or ARDS ... and/or agonal respirations
Right-Sided Heart Failure - Differential Diagnosis Algorithm
Cardiac Causes - Rule out Left-Sided Heart Failure (Most Common):
• Diffuse Lung ... Disease • Acute ... Respiratory Distress ... Syndrome ... • Chronic Lung Infection
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
organizing pneumonia, ARDS ... toxicity (e.g., acute ... respiratory distress ... syndrome) is rare ... Exclude other causes