14 results
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... less systemic symptoms ... , holster sign, ... anti-synthetase syndrome ... Myositis #diagnosis #rheumatology
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Common Causes: • Autoimmune ... pseudomonas) Autoimmune ... clue • Blood tests ... addisons #disease #endocrinology ... #diagnosis #signs
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
and signs. ... Symptoms: Tiredness ... Carpal timel syndrome ... #PhysicalExam # ... Endocrinology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral infection, autoimmune ... CLL (older) • Autoimmune ... • Diagnostic Test ... Donath-Landsteiner test
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
meningitis), MCC CNS symptoms ... Positive pathergy test ... is a skin prick test ... diagnosis #management #signs ... #symptoms #rheumatology
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
Cause in the US: Autoimmune ... ketoconazole, etomidate) Symptoms ... hypophysitis, Sheehan's syndrome ... A STIM test can ... Diagnosis #Management #Endocrinology
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
virus or Group A Strep ... by neutrophilic autoimmune ... nephrotic/nephritic syndrome ... Pathophysiology #Diagnosis #Signs ... #Symptoms
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
adults in the west ... with no early symptoms ... Physical Exam/Signs ... • Richter’s Syndrome ... leukemia • Sezary syndrome
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
Cushing's Syndrome ... dexamethasone suppression test ... #Cushings #Syndrome ... Hypercortisolism #Diagnosis #signs ... #symptoms #endocrinology
Newborn Infant - Routine Examination

Birthweight, gestational age and birthweight percentile are noted.
General observation Of the baby's
is also a late sign ... assessment, is best ... are observed for signs ... of respiratory distress ... Newborn #Infant #PhysicalExam