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diagnosis management signs disease erythematosus hematology lupus systemic agglutinin anemia arteritis autoimmune behcet chronic classification cll cold gca hemolytic leukemia
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behcet disease) Differential ... Oral aphthae : SLE ... • Arthritis: SLE ... diagnosis #management #signs ... #symptoms #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Presentation - Systemic Symptoms ... purpura: strong sign ... retinopathy Lab Tests ... , and SLE) • Urinalysis ... #rheumatology #
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Butterfly rash, Vasculitis ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... diseases, such as SLE ... purpura: Strong sign ... • Progressive symptoms ... Diagnosis #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... ANCA-associated vasculitis ... Non-autoimmune rheumatologic ... Induced Lupus: • Symptoms ... Erythematosus #Diagnosis #Rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... very remarkable w/differential ... the “Chewing gum test ... them, but urgent rheumatology ... #GiantCell #arteritis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Cold Agglutinin Syndrome ... younger pts) Differential ... • Diagnostic Test ... Donath-Landsteiner test
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... adults in the west ... with no early symptoms ... Physical Exam/Signs ... • Richter’s Syndrome
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Bilateral signs ... and/or symptoms ... negative, MOG-IgG test ... - Sjogren - Vasculitis ... management #neurology #differential
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... Diagnostic Tests ... papules and Gottron sign ... ) • Shawl sign ... #differential #
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