15 results
Diagnosing Vitamin B12 and/or Folate Deficiency

It turns out that simply measuring serum levels of B12 or
Diagnosing Vitamin ... stores have normal ... tissue stores. ... tissue folate stores ... #Hematology #ComparisonTable
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Megakaryopoiesis • B12 ... Deficiency • ... Quinidine • HIT ... Algorithm #Causes #Hematology
Iron Deficiency Anemia (IDA)
Tests:
 • MCV/RBC - RBC ↓ in proportion to the ↓ in hemoglobin
Iron Deficiency ... Anemia (IDA) Tests ... total body iron stores ... #Fe #diagnosis ... #hematology
Etiologies of Folate Deficiency
 • Decreased dietary intake - uncommon in this era
 • Increased requirements
have hemolytic anemia ... mobilize folate stores ... depleted tissue stores ... #differential #diagnosis ... #hematology #nutrition
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... intrinsic factor, IF) Clinical ... , yellow skin, cognitive ... palpitations), skin ... large total body stores
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... Headaches • Pale skin ... , GATA2 deficiency ... #oncology #hematology ... #diagnosis #management
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
- Differential Diagnosis ... Capitis - Skin ... Examine the entire skin ... texture at bald spots ... #dermatology #Hairloss
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... - Hemolytic anemia ... necrosis) • VIT K deficiency ... #hematology #rheumatology ... #nonpalpable #dermatology
Vibrio Vulnificus skin infection
Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. 
Vibrio vulnificus part of
Vibrio Vulnificus skin ... cellulitis w/ black spots ... hemochromatosis, hemolytic anemia ... rash #cellulitis #dermatology ... #legs #clinical
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Bandemia, AKI. ... tissue (Staph/Strep ... the key to the diagnosis ... #Rash #dermatology ... #clinical #photo