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diagnosis differential algorithm acute aki diseases kidney nephritic glomerulonephritis microscopy proteinuria syndrome atlas casts hematuria key kidneyinjury locations membranoproliferative mpgn
Spectrum of Glomerular Diseases Nephrotic - Mechanism: • Injury to podocytes • Changed architecture: Scanning. Deposition of
Spectrum of Glomerular ... Mechanism: • Injury ... • Breaks in GBM ... spectrum #diagnosis #nephrology ... #comparison
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
Glomerular Diseases ... to GBM disruption ... diabetes)) #Glomerular ... #Classification ... #Proteinuria #Nephrology
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
Nephritic vs Nephrotic ... the patient have glomerular ... hematuria (RBC casts ... #Syndrome #Comparison ... #Algorithm #Nephrology
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... benign sediment (injury ... • Hereditary nephritis ... and >3.5g/day (nephrotic ... ) proteinuria (injury
Causes of acute kidney injury (AKI). AKI is classified into pre-renal, renal, and post-renal causes. Renal
kidney injury (AKI ... vascular supply; glomerular ... GBM, Glomerular ... Acute #Kidney #Injury ... #Sites #Nephrology
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
with evidence of glomerular ... immune deposits in glomeruli ... nephropathy, lupus nephritis ... Glomerulonephritis #RPGN #Classification ... Differential #Diagnosis #Nephrology
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
- Classification ... - TTP/HUS • Glomerular ... tubular necrosis (causes ... Acute interstitial nephritis ... #diagnosis #nephrology
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
abnormalities of selected glomerular ... ) Haematuria/nephritis ... polyangiitis #glomerular ... #diseases #nephrology ... #pathology #comparison
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
Acute tubular injury ... red - cells Non-glomerular ... brown cast” - Necrotic ... acute tubular injury ... key #diagnosis #nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Cytomegalovirus; GBM ... clusters because nephritic ... Nephrocalcinosis causes ... #proteinuria #nephrotic ... #syndrome #nephrology
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