13 results
Stevens-Johnson syndrome (SJS), Toxic epidermal necrolysis (TEN) and Overlap

 SJS-TEN overlap and TEN - Surface Epidermal
Stevens-Johnson syndrome ... overlap and TEN ... Stevens #Johnsons #Syndrome ... Epidermal #Necrolysis #Comparison ... #Diagnosis #Dermatology
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
Nikolsky's Sign ... Epidermal Necrolysis (TEN ... Stevens-Johnson Syndrome ... Staphylococcal scalded skin syndrome ... #TEN #Dermatology
DRESS Syndrome vs SJS/TEN
DRESS
 • Latency: 2-8 weeks
 • Rash: Morbilliform
 • Mucosal involvement: 50% have
DRESS Syndrome vs ... SJS/TEN DRESS ... SCVMCMed #DRESS #Syndrome ... #SJS #TEN #comparison ... #table #dermatology
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
the Nikolsky sign ... substantially, usually to TEN ... staphylococcal scalded skin syndrome ... and toxic shock syndrome ... #Diagnosis #Dermatology
Management of Serotonin Syndrome
Identify and stop all serotoninergic medications
 • Avoid inadvertent Rx of serotoninergic meds
Management of Serotonin ... Syndrome Identify ... normalize vital signs ... loading dose, then ... #Management #treatment
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
reaction • SJS/TEN ... Exanthematous Pustulosis Management ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis ... #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... hyperviscosity syndrome ... WBC >100k, + lab signs ... TLS #diagnosis #management ... #hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... SAPHO syndrome is ... and if negative then ... Rheumatology #diagnosis #management ... #Dermatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... Diagnosis: HLH signs ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
Signs of poor perfusion ... Signs of congestion ... acute coronary syndrome ... with emphasis then ... differential #algorithm #management