20 results
Clinical manifestations of acute liver failure 

Brain: 
Hepatic encephalopathy,  
Cerebral edema,  
Intracranial hypertension,
Clinical manifestations ... of acute liver ... Intracranial hypertension ... lung injury, ... Signs #Symptoms #Diagnosis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... ACLF) Clinical Guidelines ... Injury (DILI) ... gastroenterology #management ... #diagnosis
Hypertensive Disorders of Pregnancy
Chronic Hypertension:
 • Guidelines as SBP ≥130 or DBP ≥ 90 mmHg
 •
evidence of organ injury ... pits <100k), ↑ liver ... finding of organ injury ... so have high clinical ... obstetrics #cardiology #differential
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
Guide to Acute Kidney ... Injury (AKI) ... - Recent hypo/hypertension ... - TTE/liver fxn? ... AKI #Nephrology #Diagnosis
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
- Workup and Differential ... Diagnosis Approach ... kidney injury). ... 109 mm Hg) with clinical ... #Diagnosis #indications
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Portal Hypertension ... - Differential ... Diagnosis Portal ... >10 mmHg - clinically ... • Cirrhosis/acute
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... headache, malaise) → Acute ... infiltration) Differential ... Diagnosis: Viral ... Maternal Support - Critical
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
weeks • Typical clinical ... and hemorrhage Acute ... obstetrics #hepatitis #comparison ... #differential # ... diagnosis #icp #
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
cycle found in the liver ... gastrointestinal distress and acute ... kidney injury are ... presentation - Clinical ... #Management
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
subclinical disease to acute ... liver failure ... hepatocellular pattern of liver ... injury, though ... #Management #Hepatology